So-called Disclosure of Pfizer’s Vaccine Trials Are Misinterpreted

In today’s Medium article, I’ll address a false claim where individuals online have stated that the vaccine is illegal and misinterpreting information on why transmission via any vaccine trials never happens. Without further ado let’s get into the article.

SARS-CoV-2 virus

➡️ The Misinterpretation of Transmission Claims

A Pfizer representative in an interview stated the trials never tested for transmission. Vaccine clinical trials for drug approval are not meant to test transmission, that comes afterwards. Clinical trials are intended to check the safety and efficacy of new drugs and vaccines before they are approved for widespread use.

SARS-CoV-2 vaccine trials did not directly estimate vaccine efficacy against transmission [1]. However, in a study published in the ScienceDirect journal, the authors estimate that Moderna’s vaccine reduces the potential for transmission by at least 61%.

The vaccine's ability to prevent transmission was assessed during it’s rollout, via a study published [2] in the Springer science journal. The study looked at recent evidence at that time and showed that the vaccines did prevent transmission, looking at one study where vaccines had efficacy in preventing infection of 90% 14 days after the second dose and 80% 14 days after the first dose [3].

The Association of American Medical Colleges [4] indicates that — “the clinical trials were not designed to test whether any of the trial participants contracted COVID-19 but showed no symptoms.” The reason transmission was not tested during these trials was that the trial size & duration (of trials) needed to have a larger participant pool, and a longer time period was needed for trials thus the end goal would be preventing deaths (if this had happened).

This was dated: 21/10/2020, so Pfizer never lied, clinical trials for ANY vaccine never test for transmission “None of the trials currently underway are designed to detect a reduction in any serious outcome such as hospitalisations, intensive care use, or deaths. Nor are the vaccines being studied to determine whether they can interrupt transmission of the virus,” [5]

References: [1] https://www.sciencedirect.com/science/article/pii/S0264410X21007350
[2] https://link.springer.com/article/10.1007/s10787-021-00847-2
[3] https://www.nejm.org/doi/10.1056/NEJMsr2105280
[4] https://www.aamc.org/news-insights/6-myths-about-covid-19-vaccines-debunked
[5] https://www.bmj.com/company/newsroom/covid-19-vaccine-trials-cannot-tell-us-if-they-will-save-lives/

➡️ Studies Showing Prevention of Transmission

References: [1] https://www.nejm.org/doi/full/10.1056/nejmoa2116597
[2] https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00127-7/fulltext
[3] https://www.science.org/doi/10.1126/science.abl4292
[4] https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2780700
[5] https://www.medrxiv.org/content/10.1101/2022.08.08.22278547v2.full-text
[6] https://www.medrxiv.org/content/10.1101/2022.04.20.22274061v1
[7] https://www.bmj.com/content/378/bmj-2022-071502
[8] https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciac635/6653543

➡️ META-Analysis on Covid-19 Vaccines Preventing Transmission.

References: [1] https://www.frontiersin.org/articles/10.3389/fpubh.2022.873596/full
[2] https://www.bmj.com/content/377/bmj-2022-069989

➡️ Other Info on Vaccines

Below are the basics of how vaccines work, showing more evidence that vaccination in general prevents transmission and other information regarding vaccines with the quotes being used as supporting evidence.

References: [1] https://raisingchildren.net.au/babies/health-daily-care/immunisation/vaccine-immunity-how-vaccines-prevent-infectious-diseases#how-vaccines-give-you-immunity-nav-title
[2] https://ec.europa.eu/info/live-work-travel-eu/coronavirus-response/safe-covid-19-vaccines-europeans/how-do-vaccines-work_en
[3] https://coronavirus.jhu.edu/vaccines/vaccines-faq

➡️ Conclusion
It’s very easy to go into the rabbit hole of misinformation when we hold onto specific core beliefs, in regards to the claims made about transmission and vaccine trials, vaccine clinical trials were never made to estimate the efficacy of transmission, so the claims are based on unfounded misunderstandings driven by uninformed people. Do Covid-19 related vaccines prevent transmission? Yes

💥 Thanks for reading, Lawrence. Please consider a small contribution, in the form of a beer as all articles are created in my small amount of spare time: https://www.buymeacoffee.com/LawrenceRob

--

--

Get the Medium app

A button that says 'Download on the App Store', and if clicked it will lead you to the iOS App store
A button that says 'Get it on, Google Play', and if clicked it will lead you to the Google Play store
Lawrence Robinson

Passionate about evidence-based scientific information and tackling falsehoods that thrive on social media.